AHK-Cu (200mg)
$143.00 $115.00
Size: 200mg
Contents: AHK-Cu
Form: Lyophilized powder
Purity: >99%
SKU: P-AHK-CU
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AHK-Cu: A Focus on Hair and Skin Health 🔬
What is AHK-Cu?
AHK-Cu (or copper AHK) is a naturally occurring peptide composed of three amino acids: alanine, histidine, and lysine, with a copper ion. It is present in the bloodstream and is studied for its potential role in regulating the growth and development of vascular endothelial cells. The peptide is primarily researched for its potential to support skin tissue integrity and hair growth, with its actions focusing on fibroblasts—cells responsible for maintaining the extracellular matrix and secreting substances like Vascular Endothelial Growth Factor (VEGF), which promotes the formation of new blood vessels. The copper ion in AHK-Cu is believed to be involved in the synthesis of collagen and elastin, two vital proteins for skin structure, and is also suggested to have antioxidant properties.
Key Areas of Scientific Research 🧪
1. AHK-Cu and Hair Follicle Development
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Researchers believe AHK-Cu may stimulate the proliferation of dermal fibroblasts and enhance the growth of hair follicles. In a recent study, the peptide appeared to promote the elongation of hair follicles and the proliferation of dermal papilla cells (DPCs), which are specialized fibroblasts that play a key role in hair follicle growth. The study also suggested that AHK-Cu may have reduced the number of apoptotic (dying) DPCs by increasing the Bcl-2/Bax ratio, which favors cell survival. These observations suggest that AHK-Cu may stimulate hair follicle growth by both promoting proliferation and preventing cell death in DPCs. It may also upregulate VEGF, which could enhance the blood supply to hair follicles.
2. AHK-Cu and Alopecia Research
A study examined the potential of formulations containing AHK-Cu and other growth factors in cases of secondary alopecia. The experiment investigated the potential for hair growth and follicle viability. The results suggested that both formulations produced a positive response regarding hair growth in the animals and were effective when tested alongside agents associated with alopecia, which was considered encouraging enough to warrant further trials.
3. AHK-Cu and Skin Tissue Integrity
Preliminary lab studies suggest that the core AHK molecule may stimulate the growth of fibroblast cells and the production of collagen. In experiments with normal dermal fibroblasts, AHK was observed to apparently boost both cell growth and viability, while also enhancing collagen type I production. The studies indicated that AHK’s presence may have raised collagen type I production by up to threefold compared to a control group. This implies that AHK may contribute to rejuvenating the extracellular matrix and supporting skin function.
4. AHK-Cu and Antioxidative Potential
AHK-Cu is posited to have potent antioxidant qualities due to its distinct amino acid structure. Researchers suggest its potential role in boosting dermal cell multiplication and survival, which are essential for collagen production. Increased cell activity provided by AHK-Cu may facilitate the process of skin cell turnover and function.
Product Specifications 📊
Molecular Formula: C15H25CuN6O4
Molecular Weight: 416.9 g/mol
Other known titles: ALA-HIS-LYS-CU, L-Alanyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]copper Monohydrochloride
Important Notice: AHK-Cu peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.