CJC-1295 & Ipamorelin Blend (10mg)
$75.00 $40.00
CJC-1295 NO DAC & Ipamorelin Product Information
This product is a 10mg blend of two high-purity peptides: CJC-1295 NO DAC (5mg) and Ipamorelin (5mg). It is provided in a lyophilized powder form with a certified purity of >99%, suitable for research purposes. The SKU is P-CJCIPAM-10.
Pricing and Discounts:
5-8 units: A 5% discount is applied, with a price of $76.00 per unit.
9+ units: A 10% discount is applied, with a price of $72.00 per unit.
We also offer FREE shipping on all orders over $200.
This blend combines two synthetic peptides, CJC-1295 and Ipamorelin, that are being researched for their potential to stimulate the release of growth hormone (GH). While both are classified as growth hormone secretagogues, they appear to have distinct mechanisms of action. CJC-1295 mimics Growth Hormone-Releasing Hormone (GHRH) and acts on GHRH receptors, while Ipamorelin mimics ghrelin and acts on the GHS-R1a receptor.
Key Research Areas 🧪
1. Half-Life and Pharmacokinetics
The peptides have different half-lives, which may lead to synergistic action. Research suggests Ipamorelin has a short half-life of about 2 hours, with its potential action declining rapidly. In contrast, CJC-1295 appears to have a much longer half-life, ranging from 5.8 to 8.1 days, due to its modifications with a drug affinity complex (DAC) that allows it to bind to plasma proteins. This difference in half-life is thought to create a sustained release of GH, with Ipamorelin providing an initial pulse and CJC-1295 providing a prolonged effect.
2. GH Release and Somatotrophs
Both peptides are posited to trigger the anterior pituitary gland to secrete GH. CJC-1295's action is thought to activate intracellular signaling pathways that lead to the transcription of GH-related genes. Ipamorelin's action on the GHS-R1a receptor is believed to activate a different signaling cascade involving phospholipase C (PLC) and the release of calcium ions. Studies on CJC-1295 have also suggested that it may interact with the somatotroph cells, which produce GH, potentially increasing their proliferation.
3. Nitrogen Balance
The combined action of the peptides on GH production is suggested to lead to a positive nitrogen balance and a potential increase in lean mass. A study on Ipamorelin indicated that it might lead to a 20% decline in urea-N production, a potential marker of nitrogen processing. This suggests that the peptide may help reinstate nitrogen equilibrium, which is crucial for protein synthesis and tissue growth.
Product Specifications 📊
Molecular Formula:
CJC-1295: C152H252N44O42
Ipamorelin: C38H49N9O5
Molecular Weight:
CJC-1295: 3367.9 g/mol
Ipamorelin: 711.8 g/mol
Other Known Titles:
CJC-1295: CJC-1295 NO DAC; Mod GRF 1-29
Ipamorelin: NNC 26-0161
Important Notice: The CJC-1295 & Ipamorelin peptide blend is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.