CJC-1295 DAC (5mg)
$58.00 $32.00
CJC-1295 with DAC Product Information
Our CJC-1295 with DAC is a high-purity, synthetic peptide available in a 5mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU is P-CJC1295-5.
Pricing and Discounts:
5-8 units: Get a 5% discount at $49.40 per unit.
9+ units: Enjoy a 10% discount at $46.80 per unit.
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CJC-1295 DAC Peptide: A Focus on Growth Hormone and IGF-1 Regulation 🔬
What is CJC-1295 DAC?
CJC-1295 DAC is a synthetic 29-amino acid analog of Growth Hormone-Releasing Hormone (GHRH). Researchers posit that it functions similarly to GHRH, potentially increasing the endogenous production of growth hormone (GH) within an organism. The term "DAC" refers to a Drug Affinity Complex, a biochemical modification that is thought to significantly prolong the peptide's half-life by allowing it to bind to plasma proteins. This extension of the half-life from approximately 30 minutes to up to 8 days may allow for a more sustained release of GH.
Key Areas of Scientific Research 🧪
1. Mechanism of Action
Studies suggest that CJC-1295 DAC may elevate both GH and Insulin-like Growth Factor-1 (IGF-1) levels. The peptide is believed to act by binding to GHRH receptors on pituitary cells, triggering a signaling cascade that leads to the transcription of the IGF-1 gene. IGF-1 is considered a key anabolic hormone that mediates many of the growth-promoting effects of GH, including protein synthesis and cellular proliferation. Research has shown that a single dose of CJC-1295 DAC may increase GH levels by 2- to 10-fold and IGF-1 levels by 1.5- to 3-fold for several days.
2. Body Composition
Animal studies suggest that CJC-1295 DAC may positively impact body composition. In murine models with a GHRH gene deletion, the peptide appeared to help preserve normal levels of lean mass while not impacting, or even reducing, fat tissue levels. This suggests that CJC-1295 DAC might promote muscle and bone structure without increasing fat accumulation. The peptide is also thought to increase the proliferation of somatotroph cells, which are the cells in the pituitary gland that produce growth hormone.
3. Half-Life and Stability
The DAC component is the primary feature of this peptide. GHRH has a half-life of about 7 minutes, while CJC-1295 without DAC has a longer half-life of 30 minutes due to four amino acid substitutions. These substitutions are believed to improve the peptide's stability against enzymatic degradation. The addition of the DAC component may extend the half-life to approximately 6-8 days, which could allow for less frequent administration in research protocols.
Product Specifications 📊
Molecular Formula: C152H252N44O42
Molecular Weight: 3367.95 g/mol
Other Known Titles: Tetrasubstituted GRF 1-29 with DAC
Important Notice: CJC-1295 DAC peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.