Melanotan 2 (10mg)


$39.00 $21.00

Melanotan 2 Product Information

Our Melanotan 2 is a high-purity, synthetic peptide available in a 10mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU is P-MELANTN2-10.

Pricing and Discounts

  • 5-8 units: Get a 5% discount at $38.95 per unit.

  • 9+ units: Enjoy a 10% discount at $36.90 per unit.

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Melanotan 2 (MT-II) is a synthetic peptide that is an analog of the α-melanocyte-stimulating hormone (α-MSH). It is a cyclic heptapeptide that is being researched for its potential to selectively bind to four of the five melanocortin receptors (MC-Rs). This non-selective binding may lead to a range of potential effects beyond skin pigmentation, including the regulation of appetite and various types of arousal.

Key Research Areas 🔬

1. Melanogenesis and Sunless Tanning

  • Mechanism: Melanotan 2 is posited to bind to the melanocortin 1 receptor (MC1R), which is expressed in melanocytes. This interaction is believed to stimulate the production of eumelanin, the pigment responsible for darkening the skin.

  • Studies: Research suggests that Melanotan 2 may induce increased skin pigmentation without the need for ultraviolet (UV) exposure. This has led to studies on its potential as a sunless tanning model.

2. Nerve Cell Regeneration and Neuroprotection

  • Mechanism: The peptide is being researched for its potential neurotrophic and neuroprotective properties, possibly mediated through its interaction with the melanocortin 4 receptor (MC4R).

  • Studies: A study on a murine model with peripheral nerve injury suggested that Melanotan 2 may promote the recovery of sensory function and protect nerves from chemically induced neurotoxicity. Researchers hypothesize that the peptide may influence neuronal structures, promoting neurite outgrowth and nerve sprouting in damaged regions.

3. Arousal Neurosignaling

  • Mechanism: When Melanotan 2 binds to the MC4R, it is hypothesized to influence the supraspinal centers in the brain, which may lead to increased arousal. These signals may then be transmitted to sympathetic and parasympathetic centers.

  • Studies: A clinical study suggested that Melanotan 2 may induce increased arousal neurosignaling in a significant percentage of cases compared to a placebo. Researchers believe its action may be linked to downstream neuromodulators like dopamine and oxytocin.

4. Neurodevelopmental Modulation

  • Mechanism: Researchers suggest that Melanotan 2 may influence neural mechanisms by stimulating neuron populations that govern social cognition, possibly through endogenous oxytocinergic signaling.

  • Studies: By potentially engaging MC4R-sensitive circuits, Melanotan 2 might trigger the release of oxytocin, which could modulate the activity of neurotransmitters like serotonin and dopamine. This may be an avenue for research into neurodevelopmental contexts.

Product Specifications 📊

  • Molecular Formula: C50​H69​N15​O9​

  • Molecular Weight: 1024.19 g/mol

  • Other Known Titles: MT-II

Important Notice: Melanotan 2 peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.