Mod GRF 1-29 & Ipamorelin Blend (10mg)
$75.00 $54.00
Mod GRF 1-29 & Ipamorelin Product Information
This product is a 10mg blend of two high-purity peptides: Mod GRF 1-29 (5mg) and Ipamorelin (5mg). It is provided in a lyophilized powder form with a certified purity of >99%, making it suitable for research applications. The SKU is P-MODGRFIPAM-10.
Pricing and Discounts
5-8 units: A 5% discount is applied, with a price of $79.80 per unit.
9+ units: A 10% discount is applied, with a price of $75.60 per unit.
We also offer FREE shipping on all orders over $200.
Mod GRF 1-29 and Ipamorelin are synthetic peptides being researched as a blend for their potential synergistic effect on stimulating the release of growth hormone (GH). They are believed to act on different receptors to achieve this effect.
1. Mechanisms of Action 🧪
The blend is composed of two different types of peptides that act on distinct receptors in the pituitary gland.
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Mod GRF 1-29: This peptide is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH). It is hypothesized to bind to GHRH receptors on somatotroph cells, triggering a cascade of intracellular signals that may lead to the release of GH.
Ipamorelin: This is a synthetic peptide classified as a growth hormone secretagogue (GHS). It is thought to mimic the action of ghrelin by activating ghrelin receptors (GHS-R1a) in the anterior pituitary gland. This action may also lead to GH secretion.
Unlike some other GHSs, Ipamorelin is being researched for its high selectivity, as it does not appear to significantly influence the release of other pituitary hormones such as prolactin, ACTH, or cortisol.
2. Research and Clinical Studies 🔬
Growth Hormone Secretion
Synergistic Effect: When used as a blend, the peptides are believed to have a synergistic effect, potentially yielding a greater release of GH than either peptide alone. Studies on rat pituitary glands and anesthetized rats suggested that these peptides are strong agonists for GHRP-like receptors and may help secrete higher concentrations of GH.
Potency: Preliminary studies suggested that Mod GRF 1-29 may be more potent than its unmodified counterpart, GRF 1-29.
Gastrointestinal and Metabolic Effects
Gastric Emptying: Research on Ipamorelin suggests it may have the potential to accelerate the process of gastric emptying and enhance the contractility of gastric smooth muscles.
Appetite and Weight Gain: Ipamorelin's potential action on ghrelin receptors has led to research on its impact on appetite. A study reported that subjects exposed to Ipamorelin experienced an increase in body weight, which researchers theorized may be linked to increased food intake.
Bone Density
Bone Mineral Content: A study on murine models suggested that Ipamorelin might be linked to an increase in weight and a possible uptick in bone mineral content in the tibia and vertebrae. The observed increase in bone mineral content appeared to be due to an enlargement in the bone's cross-sectional area.
3. Product Information 🧬
Modified GRF 1-29:
Molecular Formula: C152H252N44O42
Molecular Weight: 3367.95 g/mol
Other Titles: CJC-1295 without DAC
Ipamorelin:
Molecular Formula: C38H49N9O5
Molecular Weight: 711.86 g/mol
Other Titles: Ipamorelin Acetate
Important Notice: This peptide blend is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.