N-Acetyl Selank (10mg)
$55.00 $41.00
N-Acetyl Selank Product Information
Our N-Acetyl Selank is a high-purity, synthetic peptide available in a 10mg size. Provided in a lyophilized powder form with a certified purity of >99%, it is intended for research purposes. The SKU is N-Acetyl-Selank.
Pricing and Discounts
5-8 units: A 5% discount is applied, with a price of $67.45 per unit.
9+ units: A 10% discount is applied, with a price of $63.90 per unit.
We also offer FREE shipping on all orders over $200.
N-Acetyl Selank is a synthetic heptapeptide being researched for its potential anxiolytic (anxiety-reducing), nootropic (cognition-enhancing), and immunomodulatory properties. It is an analog of the naturally occurring peptide Tuftsin and is structurally modified with an acetyl group and a Pro-Gly-Pro fragment, which may enhance its stability and ability to cross the blood-brain barrier (BBB).
1. Mechanisms of Action 🧪
N-Acetyl Selank is believed to act on several key systems in the central nervous system.
GABA System: It may potentially stimulate the gamma-aminobutyric acid (GABA) system, which is the brain's primary inhibitory neurotransmitter system. By influencing genes related to GABA receptors and transporters, it might reduce neuronal excitability and alleviate anxiety.
Serotonin Signaling: The peptide is also thought to interact with serotonin signaling, a system that regulates mood and anxiety. Studies suggest it may enhance serotonin metabolism in the brainstem, potentially correcting disturbances related to reduced serotonin function.
Enkephalin Signaling: N-Acetyl Selank is posited to inhibit enzymes that degrade enkephalins, which are natural pain relievers and mood modulators. This action could increase the availability of enkephalins, potentially amplifying their effects.
BDNF Expression: It may also affect the expression of brain-derived neurotrophic factor (BDNF), which is crucial for neuroplasticity. Selank has been suggested to elevate BDNF mRNA levels in the hippocampus, a brain region involved in memory and learning.
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2. Research and Clinical Studies 🔬
Anxiolytic and Nootropic Potential
Anxiety: In clinical studies, Selank was found to be as effective as some allopathic compounds in reducing anxiety levels in models of generalized anxiety disorder. It also appeared to have positive psychostimulant and nootropic effects.
Cognition: Research on murine models suggested that Selank may improve learning and memory by reducing the number of errors in conditioned avoidance response (CAR) exercises. This effect is hypothesized to be linked to its ability to enhance neural plasticity and reduce anxiety.
Immunomodulation
Immune Response: Studies have suggested that Selank may act as an immunomodulator. In models of anxiety and neurasthenia, the peptide appeared to cause a rise in interleukin-6 cytokines and altered the Th1 to Th2 cytokine ratio, hinting at a potential to help the body adapt to environmental stressors.
Additional Research Areas
Substance Withdrawal: In murine models of alcohol withdrawal, the peptide appeared to reduce withdrawal symptoms after 48 hours.
Cholesterol Control: A study on mice on a high-fat diet suggested that Selank might improve fat metabolism and reduce total cholesterol, LDL, VLDL cholesterol, and triglycerides.
3. Product Information 🧬
Molecular Formula: C33H57N11O9
Molecular Weight: 751.9 g/mol
Other known titles: TP-7, Selanc
Important Notice: N-Acetyl Selank peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.