N-Acetyl Selank (10mg)
$79.00$71.00
N-Acetyl Selank is a synthetic heptapeptide that is an analog of the naturally occurring peptide Tuftsin. It is being researched for its potential nootropic (cognitive-enhancing) and anxiolytic (anxiety-reducing) effects. The peptide contains a Pro-Gly-Pro fragment that may enhance its ability to cross the blood-brain barrier (BBB), and the N-acetyl group is thought to improve its stability against enzymatic degradation.
Product Information
Specification | Details |
SKU | N-Acetyl-Selank |
Purity | >99% |
Form | Lyophilized powder |
Size | 10mg |
Contents | N-Acetyl Selank |
Pricing
Quantity | Discount | Price (USD) |
Single Unit | N/A | $71.00 |
5 - 8 | 5% | $67.45 |
9+ | 10% | $63.90 |
Chemical Makeup
Specification | Details |
Molecular Formula | C_33H_57N_11O_9 |
Molecular Weight | 751.9 g/mol |
Other Known Titles | TP-7, Selanc |
Research and Clinical Studies
While research on N-Acetyl Selank is limited, studies on its non-acetylated form, Selank, suggest several potential mechanisms of action.
Anxiolytic & Nootropic Actions
Research suggests Selank may have both anxiolytic and nootropic potential. In a clinical study on models with generalized anxiety disorder, the peptide appeared to reduce anxiety levels similarly to a control compound (5). It is thought to work by modulating several key systems in the brain:
GABA System: Selank is believed to stimulate gamma-aminobutyric acid (GABA) receptors, an inhibitory neurotransmitter that reduces neuronal excitability and promotes relaxation (2).
Serotonin Signaling: The peptide may also modulate serotonin levels and metabolism in the brain, which are crucial for regulating mood and anxiety (3).
Enkephalin Signaling: Selank may inhibit enzymes that degrade enkephalins, which are natural opioid peptides that play a role in pain perception and mood modulation (4, 5).
BDNF Expression: Research suggests Selank may elevate brain-derived neurotrophic factor (BDNF) mRNA levels in the hippocampus, a brain region critical for learning and memory, potentially enhancing neural plasticity (8).
A study on mice undergoing training for conditioned avoidance response suggested that Selank might improve learning abilities and reduce errors, pointing to its nootropic potential (10).
Immunomodulation
In models with anxiety and neurasthenia, Selank appeared to cause a significant rise in levels of interleukin-6 cytokines and alter the Th1 to Th2 cytokine ratio (11). This suggests that Selank may function as an immunomodulator, potentially helping to regulate the body's response to stressors.
Metabolic & Substance Withdrawal Research
Research has also explored Selank's potential in other areas. In studies on mice with a high-fat diet, the peptide appeared to improve fat metabolism and reduce cholesterol levels, suggesting it may have a role in modulating lipid metabolism (13).
Additionally, in models with alcohol withdrawal symptoms, Selank reportedly reduced these symptoms within 48 hours, indicating a potential role in managing substance withdrawal (12).
Disclaimer: N-Acetyl Selank peptide is available for research and laboratory purposes only.
