N-Acetyl Semax (25mg)
$68.00$60.00
N-Acetyl Semax is a synthetic polypeptide analog of the adrenocorticotropic hormone (ACTH) that is being investigated for its potential nootropic and neuroprotective effects. It is a modified version of the peptide Semax, with an N-acetyl group that is thought to improve its stability and a Pro-Gly-Pro (PGP) extension that may enhance its ability to cross the blood-brain barrier (BBB).
Product Information
Specification | Details |
SKU | N-Acetyl-Semax |
Purity | >99% |
Form | Lyophilized powder |
Size | 25mg |
Contents | N-Acetyl Semax |
Pricing
Quantity | Discount | Price (USD) |
Single Unit | N/A | $60.00 |
5 - 8 | 5% | $57.00 |
9+ | 10% | $54.00 |
Chemical Makeup
Specification | Details |
Molecular Formula | C_37H_51N_9O_10S |
Molecular Weight | 858.97 g/mol |
Other Known Titles | ACTH (4-7)PGP, HY-P1146 |
Research and Clinical Studies
While research on N-Acetyl Semax specifically is limited, studies on its un-acetylated counterpart, Semax, suggest several potential actions.
Nootropic & Anxiolytic Potential
Research suggests that Semax may have a positive impact on cognitive function and anxiety. It is believed to work by influencing several systems in the brain:
Neurotransmitters: Studies indicate that Semax may increase the striatal levels of a serotonin metabolite, suggesting an enhancement of serotonergic activity. The peptide may also modulate the dopaminergic system's responsiveness (5).
Enkephalins: Semax may inhibit enzymes that degrade enkephalins, which could increase the levels of these endogenous opioids that are involved in stress response and pain perception (2).
In a study on rodents, Semax appeared to enhance memory and attention in models under excessive stress (7). In another study on rats with maternal deprivation, the peptide reportedly reduced anxiety and normalized their activity levels, which suggests a potential role in alleviating separation anxiety (9).
Neuroprotection & Cardiovascular System
Semax is also being investigated for its neuroprotective potential. In a clinical study on models of ischemic strokes, those exposed to Semax in addition to conventional compounds reportedly showed notable improvement in restoring damaged brain activity (11).
Research also suggests that the peptide may offer protection to the cardiovascular system. A study on rodents with induced myocardial infarction reported that models exposed to Semax appeared to show prevention of diastolic blood pressure, which may indicate a remodeling of the heart ventricle and inhibition of heart failure (10).
Disclaimer: N-Acetyl Semax peptide is available for research and laboratory purposes only.
