Pal-AHK (200mg)
$147.00 $126.00
Pal-AHK Product Information
Our Pal-AHK is a high-purity, synthetic peptide available in a 200mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU for this product is P-Pal-AHK.
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Pal-AHK, or Palmitoyl AHK, is a synthetic peptide composed of alanine, histidine, and lysine with an added palmitoyl group. The palmitoyl group is believed to enhance the peptide's ability to penetrate cells. Research on its non-palmitoylated counterpart, AHK, suggests that Pal-AHK may have potential to stimulate collagen and elastin production, exhibit antioxidant action, and promote hair follicle growth.
1. Mechanisms of Action 🧪
The potential actions of Pal-AHK are hypothesized to be multifaceted:
Stimulating Collagen Production: AHK is thought to increase the proliferation of dermal fibroblasts, which are the cells responsible for producing collagen. It may also directly increase collagen type I production.
Antioxidant Effects: The peptide's unique amino acid composition may allow it to act as an antioxidant, neutralizing free radicals and potentially reducing oxidative stress. It is also believed to reduce the expression of TGF-β1, a molecule that can contribute to chronic inflammation.
Promoting Hair Growth: Research on AHK derivatives suggests they may promote hair growth by:
Preventing Apoptosis: Elevating the Bcl-2/Bax ratio, which may inhibit the programmed cell death of dermal papilla cells (DPCs), and reducing levels of pro-apoptotic proteins like caspase-3 and PARP.
Enhancing Blood Supply: Increasing the expression of vascular endothelial growth factor (VEGF), a protein that promotes the growth of blood vessels around hair follicles.
2. Research and Clinical Studies 🔬
Skin and Hair Health
Skin Cells: In cell culture studies, AHK appeared to increase the viability and growth of dermal fibroblasts and was reported to boost collagen type I production by up to 300% compared to a control. This suggests the peptide may help to renew the extracellular matrix of the skin.
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Hair Growth: While there is no direct research on Pal-AHK's effect on hair, studies on similar compounds suggest they may promote the elongation of hair follicles and the proliferation of dermal papilla cells.
3. Product Information 🧬
Molecular Formula: C31H56N6O5
Molecular Weight: 592.8 g/mol
Other Known Titles: Palmitoyl AHK
Important Notice: Pal-AHK peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.