Palmitoyl Tetrapeptide-7 (200mg)
$127.00 $105.00
Palmitoyl Tetrapeptide-7 Product Information
Our Palmitoyl Tetrapeptide-7 is a high-purity, synthetic peptide available in a 200mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU for this product is P-PAL-TETRA-7
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Palmitoyl Tetrapeptide-7 is a synthetic peptide composed of four amino acids (glycine, glutamine, and arginine) attached to a palmitoyl group. It is an analog of natural matrikine peptides, which are being researched for their potential to regulate the turnover of the extracellular matrix (ECM). The added palmitoyl group is believed to enhance the peptide's penetration through the skin barrier.
1. Mechanisms of Action 🧪
The peptide is hypothesized to function in several ways to support skin health:
ECM Synthesis: It is thought to stimulate the production of key ECM components, such as collagen and elastin. Specifically, it may target the synthesis of collagen VII, which is crucial for the structural integrity of the dermal-epidermal junction.
Inhibiting Inflammation: Palmitoyl Tetrapeptide-7 may suppress the production of interleukin-6 (IL-6), a pro-inflammatory cytokine that can contribute to skin cell aging and inflammation.
Inhibiting Degradation: The peptide is also suggested to potentially inhibit the activity of matrix metalloproteinases (MMPs), which are enzymes that degrade ECM proteins. By downregulating MMPs, it may help preserve the integrity of skin tissue.
2. Research and Clinical Studies 🔬
Skin Health and Anti-Aging
Wrinkle Reduction: Clinical studies have shown that Palmitoyl Tetrapeptide-7 may reduce the depth and length of wrinkles. A study reported a 14.07% reduction in fine wrinkles after four weeks of application.
Skin Elasticity: The peptide also appears to increase skin elasticity. One study reported an increase in skin elasticity of 8.79% after four weeks.
Synergistic Effects: Research suggests that when combined with Palmitoyl Oligopeptide (as in the product Matrixyl 3000), the two peptides may have a synergistic effect on stimulating collagen production and reducing inflammation.
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Other Research Areas
Oral Conditions: Due to its potential to inhibit MMPs, researchers are exploring its possible use in mitigating oral conditions like periodontitis, which is characterized by the breakdown of periodontal tissues by excessive MMP activity.
Skin Damage: By potentially stimulating collagen synthesis and inhibiting inflammation, the peptide is being researched for its potential to reduce damage caused by environmental factors like UV radiation.
3. Product Information 🧬
Molecular Formula: C34H62N8O7
Molecular Weight: 694.9 g/mol
Other Known Titles: Pal-Gly-Gln-Pro-Arg-OH, N-Palmitoylrigin, Palmitoyl-GQPR, Rigin
Important Notice: Palmitoyl Tetrapeptide-7 is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.