Pentapeptide-18 (Leuphasyl) (200mg)
$121.00 $105.00
Pentapeptide-18 Product Information
Our Pentapeptide-18 is a high-purity, synthetic peptide available in a 200mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU for this product is P-Pentapeptide-18.
We also offer FREE shipping on all orders over $200.
Sources
Pentapeptide-18 (Leuphasyl) is a synthetic peptide composed of five amino acids. It is being researched for its potential to reduce the appearance of wrinkles and fine lines by acting on the mechanisms of muscle contraction. Researchers hypothesize that it may mimic the body's natural processes for suppressing muscle contractions.
1. Mechanisms of Action 🧪
Pentapeptide-18 is believed to work by influencing neural signaling pathways that control muscle activity, particularly in the skin.
Neurotransmitter Modulation: It is hypothesized to interact with neuroreceptors to potentially inhibit the release of acetylcholine, a neurotransmitter that triggers muscle contractions. This may lead to reduced muscle contractions, which in turn could decrease the formation and depth of wrinkles.
Enkephalin Mimicry: The peptide is thought to mimic the action of enkephalins, which are endogenous opioid peptides that regulate neurotransmitter release. This action may involve the modulation of calcium influx into neurons, a process crucial for neurotransmitter secretion.
Glutamate Reduction: In some studies, the peptide appeared to reduce the release of glutamate, an excitatory neurotransmitter, which could also contribute to decreased muscular activity beneath the skin.
Licensed by Google
2. Research and Clinical Studies 🔬
Wrinkle and Fine Line Reduction
Wrinkle Depth: A 2014 study on moderate to severe wrinkles showed an average reduction in wrinkle depth of 11.31% after 28 days of twice-daily application of a Pentapeptide-18 formulation.
Overall Improvement: Clinical studies have suggested a statistically significant reduction in the appearance of wrinkles ranging from 2% to 9%.
Skin Smoothness: In a randomized, double-blind, placebo-controlled study, researchers reported an overall increase in skin smoothness after four weeks of peptide exposure.
Additional Research Potential
Melanogenesis: Research is exploring modified versions of Pentapeptide-18, specifically with D-tyrosine substitutions. Preliminary findings suggest that these modifications may reduce melanogenesis (the synthesis of melanin), hinting at a potential role in addressing skin pigmentation.
3. Product Information 🧬
Molecular Formula: C29H39N5O7
Molecular Weight: 569.65 g/mol
Other Known Titles: H-Tyr-Ala-Gly-Phe-Leu-OH, Leuphasyl
Important Notice: Pentapeptide-18 peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.