Selank (10mg)
$59.00$52.00
Selank is a synthetic heptapeptide (seven amino acids) that is being investigated for its potential to impact the central nervous system and immune function. It is a derivative of the naturally occurring peptide Tuftsin and contains a Pro-Gly-Pro (PGP) sequence that is thought to enhance its ability to cross the blood-brain barrier.
Product Information
Specification | Details |
SKU | P-SELANK-10 |
Purity | >99% |
Form | Lyophilized powder |
Size | 10mg |
Contents | Selank (10mg) |
Pricing
Quantity | Discount | Price (USD) |
Single Unit | N/A | $52.00 |
5 - 8 | 5% | $49.40 |
9+ | 10% | $46.80 |
Chemical Makeup
Specification | Details |
Molecular Formula | C_33H_57N_11O_9 |
Molecular Weight | 751.88 g/mol |
Other Known Titles | TP-7, Selanc |
Research and Clinical Studies
Neurological & Behavioral Effects
Selank's research potential is focused on its effects on the brain. Studies suggest it may increase levels of brain-derived neurotrophic factor (BDNF), a protein that supports neuronal survival and growth. This could be relevant for research into neuroplasticity (1). It is also being investigated for its potential to influence serotonin signaling, which is crucial for mood and anxiety regulation, by boosting serotonin metabolism in the brainstem (10).
Selank may also affect the GABAergic system. In a study on murine models, Selank's effects on gene expression were found to positively correlate with those of GABA, an inhibitory neurotransmitter that plays a role in reducing neuronal excitability and mitigating anxiety (7). The peptide's potential influence on memory and learning has also been explored, with a study on murine models suggesting that Selank exposure may improve learning abilities and reduce errors in a conditioned avoidance response (CAR) test (11).
In a clinical study on models with Generalized Anxiety Disorder (GAD), Selank's impact was reported to be similar to a generic benzodiazepine compound. The study also reported that Selank appeared to reverse reduced levels of enkephalins, which are endogenous opioid peptides involved in regulating pain, mood, and stress responses (9).
Immunomodulation & Metabolism
Selank is being researched for its potential to regulate the immune system. A study on models of GAD with neurasthenia reported that Selank exposure led to a peak elevation in the levels of the IL-6 cytokine and changes in the Th1 and Th2 cytokine ratio, which are both involved in immune regulation (12).
Furthermore, studies on murine models have suggested that Selank may influence metabolism. In one study, models on a high-fat diet exhibited a gradual reduction in weight and a decrease in cholesterol and fat levels after Selank exposure. This indicates a potential for the peptide to influence lipid metabolism (15).
Disclaimer: Selank peptide is available for research and laboratory purposes only.
