Semax (25mg)
$45.00 $33.00
Semax Product Information
Our Semax is a high-purity, synthetic peptide available in a 25mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU for this product is P-SEMAX-25.
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Semax is a synthetic polypeptide analog of a fragment of the adrenocorticotropic hormone (ACTH 4-7). It's being researched for its potential neuro-modulatory and neuroprotective effects, with its primary actions hypothesized to occur in the central nervous system. The addition of a Pro-Gly-Pro (PGP) sequence to its structure is believed to enhance its ability to cross the blood-brain barrier.
1. Mechanisms of Action 🧪
Semax's potential actions are believed to be multifaceted, involving several interconnected systems:
Neurotransmitter Modulation: Semax may influence key neurotransmitter systems. It's thought to inhibit enzymes that degrade enkephalins, which regulate pain and stress response. It may also elevate levels of dopamine and serotonin, which are crucial for mood, motivation, and cognitive function.
Neurotrophic Factor Enhancement: The peptide is speculated to increase levels of brain-derived neurotrophic factor (BDNF), a protein essential for neuronal survival, growth, and neuroplasticity.
Gene Expression: Semax has been speculated to alter the expression of genes that modulate the immune system, specifically those related to chemokines and immunoglobulins, which may lead to changes in immune cell activity and vascular function.
Enzyme Inhibition: The peptide is thought to inhibit certain enzymes that break down peptides, thereby extending the half-life of other biologically active molecules.
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2. Research and Clinical Studies 🔬
Neurocognitive and Mental Health
Nootropic Action: A study on Semax's nootropic potential showed that it appeared to elevate levels of 5-HIAA, a metabolite of serotonin, suggesting it might enhance serotonergic activity. Another small-scale trial suggested it may increase memory recall and focus under high-stress conditions.
Anxiety and Stress: In models of neonatal anxiety induced by SSRIs or maternal deprivation, Semax appeared to mitigate anxiety-like behaviors and restore learning abilities. Researchers hypothesized it may re-establish normal levels of monoamines in the brain.
Neuroprotection: A clinical trial on patients with ischemic stroke showed that Semax appeared to improve the rate of restoration of damaged neurological functions, as analyzed by EEG mapping.
Other Research Areas
Vascular System: A study on murine models with induced myocardial infarction suggested that Semax may protect the heart from vascular damage, potentially preventing cardiac hypertrophy and ameliorating the imbalance between contractile and mitochondrial apparatus growth.
3. Product Information 🧬
Molecular Formula: C39H54N10O10S
Molecular Weight: 854.99 g/mol
Other Known Titles: ACTH (4-7)PGP, HY-P1146
Important Notice: Semax peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.