Semax (25mg)

Semax is a synthetic polypeptide and a derivative of a fragment of the adrenocorticotropic hormone (ACTH 4-7). It has a modified structure with a Pro-Gly-Pro (PGP) sequence that is being researched for its potential to enhance its ability to cross the blood-brain barrier and increase its stability in biological systems.

Product Information

Pricing

Chemical Makeup

Research and Clinical Studies

Nootropic & Neuroprotective Action

Semax is being investigated for its potential nootropic effects on the central nervous system. Research suggests it may increase levels of 5-HIAA, a metabolite of serotonin, which could enhance serotonergic activity and affect mood, cognition, and overall brain function (6). A study also reported that Semax may induce elevated secretion of dopamine and increase levels of brain-derived neurotrophic factor (BDNF), which is crucial for neuronal survival and growth (4).

In a clinical trial on models of ischemic stroke, Semax exposure appeared to improve the rate of restoration of damaged neurological functions (10). A study on neonatal murine models with SSRI-induced anxiety reported that Semax seemed to mitigate anxiety-like behaviors and restore normal monoamine levels in the brain (7).

Vascular & Emotional Health

Research suggests that Semax may have a protective effect on the vascular system. A study on murine heart models with experimentally induced myocardial infarction reported that Semax appeared to prevent the growth of diastolic pressure in the left ventricle and ameliorate cardiomyocyte hypertrophy (8).

The peptide's potential to influence emotional and stress-related behaviors has also been explored. A study on adolescent rats that experienced maternal deprivation reported that Semax exposure seemed to restore their emotional reactions and anxiety levels to control levels (9).

Disclaimer: Semax peptide is available for research and laboratory purposes only.