Syn-Coll (Palmitoyl Tripeptide-5) (200mg)
$95.00 $86.00
Syn-COLL Product Information
Our Syn-COLL is a high-purity, synthetic peptide available in a 200mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU for this product is P-SYN-COLL.
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Syn-Coll, also known as palmitoyl tripeptide-5, is a synthetic peptide being researched for its potential anti-aging properties. It is designed to mimic the activity of thrombospondin-1 (TSP-1), a protein that stimulates transforming growth factor beta (TGF-β). Its primary mechanism of action is believed to be stimulating collagen synthesis while also preventing its breakdown.
1. Mechanisms of Action 🧪
Syn-Coll's potential actions are focused on maintaining skin integrity and structure:
Stimulating TGF-β: The peptide is believed to mimic a sequence of TSP-1 to activate the growth factor TGF-β. This activation is thought to play a vital role in stimulating collagen production.
Increasing Collagen Synthesis: By activating TGF-β, Syn-Coll may increase the production of Type I and Type III collagen by dermal fibroblasts. Studies suggest this action may be more effective than other similar peptides.
Inhibiting Collagen Breakdown: Syn-Coll may also prevent collagen degradation by inhibiting the activity of matrix metalloproteinases (MMPs), a group of enzymes like MMP-1 and MMP-3 that break down collagen and other extracellular matrix proteins.
Supporting Skin Barrier: The peptide may help prevent water loss from the skin's surface and act as a humectant and emollient, which can help maintain optimal hydration levels.
2. Research and Clinical Studies 🔬
Anti-Aging and Skin Improvement
Wrinkle Reduction: A study on Syn-Coll reported that it may exhibit a dose-dependent wrinkle reduction and could be roughly 3.5 times more effective than a placebo. Another study over 84 days suggested it may reduce wrinkle parameters by 12%.
Roughness and Texture: A study on 60 subjects over 84 days reported that twice-daily application of Syn-Coll appeared to reduce skin roughness better than control groups and other peptides.
Preventing Pigmentation: When modified with an L-ascorbate moiety, the peptide (Pal-KVK-AA) may also inhibit melanin synthesis, which could help reduce hyperpigmentation caused by photoaging and other factors.
3. Product Information 🧬
Molecular Formula: C33H65N5O5
Molecular Weight: 611.9 g/mol
Other Known Titles: Palmitoyl-lysyl-valyl-lysine, Palmitoyl Tripeptide-5
Important Notice: Syn-Coll peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.