TB-500 (Thymosin Beta 4) (5mg / 10mg)
$86.00$78.00
TB-500 (Thymosin Beta 4) is a synthetic version of the naturally occurring protein Thymosin beta 4, which is found in abundance in the thymus gland and in wound fluid. It is being researched for its potential to accelerate wound healing, promote angiogenesis (new blood vessel formation), reduce inflammation, and support tissue repair in various organs.
Product Information
Specification | Details |
SKU | P-TB500 |
Purity | >99% |
Form | Lyophilized powder |
Sizes | 5mg, 10mg |
Contents | TB-500 |
Pricing
Size | Single Unit Price (USD) | 5 - 8 Units Price Range (USD) | 9+ Units Price Range (USD) |
5mg | $78.00 | $74.10 | $70.20 |
10mg | $140.00 | $133.00 | $126.00 |
Chemical Makeup
Specification | Details |
Molecular Formula | C_212H_350N_56O_78S |
Molecular Weight | 4963 g/mol |
Other Known Titles | Thymosin Beta 4 |
Research and Clinical Studies
Wound Healing & Angiogenesis
TB-500 is extensively researched for its potential to accelerate the healing of both acute and chronic wounds. A study on wounded murine models reported that TB-500 exposure appeared to increase re-epithelialization by 41% and wound contraction by 11% (5). It has also been reported to accelerate the healing process in models of stasis and pressure ulcers by as much as one month (6).
Its potential to induce angiogenesis, or the formation of new blood vessels, is a key focus of research. Studies suggest that TB-500 may promote cell viability and migration through its interactions with the Notch and NF-κB pathways (13).
Inflammation & Tissue Repair
Research suggests that TB-500 may have anti-inflammatory properties. It is thought to potentially increase the levels of microRNA-146a (miR-146a), which may suppress inflammation-related cytokines (4).
The peptide is also being investigated for its potential to support tissue repair in various organs. In studies on cardiac health, TB-500 reportedly decreased right ventricular heart cell hypertrophy in models with pulmonary hypertension (7). It has also been explored for its potential to enhance the resilience of myocardial cells under hypoxic conditions and promote the regeneration of cardiac cells (8).
Hair Growth & Corneal Tissues
In a study on mice, researchers reported that TB-500 appeared to increase the number of hair shafts and hair follicles, thus inducing hair growth (10). Furthermore, studies have posited that TB-500 may modulate cytokine production to accelerate healing in corneal wound models. It is also theorized to possess anti-apoptotic attributes, potentially blocking caspases and curtailing the release of pro-apoptotic proteins (14).
Disclaimer: TB-500 peptide is available for research and laboratory purposes only.
