Testagen (20mg)
$78.00 $63.00
Testagen Product Information
Our Testagen is a high-purity, synthetic peptide available in a 20mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU for this product is P-TESTAGEN-20.
Pricing and Discounts
5-8 units: A 5% discount is applied, with a price of $59.85 per unit.
9+ units: A 10% discount is applied, with a price of $56.70 per unit.
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Testagen (KEDG) is a synthetic tetrapeptide belonging to the class of Khavinson peptides. It is being researched as a potential bioregulator that may interact with the anterior pituitary gland to influence endocrine pathways, specifically those related to the synthesis of testosterone and thyroid-stimulating hormone (TSH).
1. Mechanisms of Action 🧪
Testagen's potential actions are focused on endocrine and cellular regulation:
Targeting the Pituitary Gland: The peptide is based on the amino acid composition of extracts from the anterior lobe of the pituitary gland. It is hypothesized to interact with the function of pituitary gland cells, which may lead to the upregulation of testosterone and TSH production.
Epigenetic Modulation: Researchers speculate that Testagen may interact with histones—proteins around which DNA is wound. This interaction could potentially influence epigenetic mechanisms, which in turn may affect cellular activities and gene expression.
Bioregulatory Function: As a short signaling peptide, Testagen may be able to cross cell and nuclear membranes to interact directly with the DNA of target tissues, potentially influencing gene transcription and other cellular processes.
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2. Research and Clinical Studies 🔬
Hypothalamic-Pituitary-Gonadal Axis
Testosterone Production: In research models of chronic inflammation and low testosterone, Testagen appeared to lead to a potential elevation in total testosterone levels and a reduction in markers of inflammation.
Hypothalamic-Pituitary-Thyroid Axis
Thyroid Function: In hypophysectomized avian models (models with the pituitary gland removed), Testagen appeared to induce a series of changes. It was associated with an apparent increase in body weight and thyroid gland weight, as well as a reduction in thyroid follicle size and a prevention of follicular epithelium flattening.
Thyroid-Stimulating Hormone (TSH): The peptide was suggested to have an apparent stimulating impact on the growth of the thyroid capsule and to potentially normalize thyroid gland weight in aged avian models. The effects were suggested to be more pronounced in younger models compared to older ones.
3. Product Information 🧬
Molecular Formula: C17H29N5O9
Molecular Weight: 447.2 g/mol
Sequence: Lys-Glu-Asp-Gly
Other Known Titles: KEDG, Anterior pituitary peptide (APP)
Important Notice: Testagen peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.