Triptorelin (2mg)
$55.00 $54.00
Triptorelin Product Information
Our Triptorelin is a high-purity, synthetic peptide available in a 2mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU for this product is P-TRIPTORL-2.
Pricing and Discounts
5-8 units: A 5% discount is applied, with a price of $51.30 per unit.
9+ units: A 10% discount is applied, with a price of $48.60 per unit.
We also offer FREE shipping on all orders over $200.
Triptorelin is a synthetic peptide that is an agonist analog of gonadotropin-releasing hormone (GnRH). It is being researched for its potential to modulate the hypothalamic-pituitary-gonadal (HPG) axis. Its unique characteristic is its ability to either upregulate or suppress the production of hormones like luteinizing hormone (LH) and follicle-stimulating hormone (FSH) depending on the duration of exposure.
1. Mechanisms of Action 🧪
Triptorelin's potential actions are centered on the HPG axis:
Initial Upregulation: When first introduced, Triptorelin is believed to bind to GnRH receptors in the pituitary gland, which may cause a temporary surge in the synthesis and secretion of LH and FSH.
Sustained Suppression: Due to its increased stability and affinity compared to natural GnRH, prolonged exposure to Triptorelin may cause the GnRH receptors to become desensitized and downregulated. This sustained suppression is thought to lead to a significant decrease in LH and FSH release.
Downstream Hormones: The reduction in LH and FSH levels is hypothesized to lead to a corresponding decrease in the production of testosterone in males and estrogen in females. This action is being researched for its potential to suppress steroidogenesis in the ovaries and testicles.
2. Research and Clinical Studies 🔬
Hormonal Modulation
Hormonal Upregulation: A single, intermittent exposure to Triptorelin may induce a temporary surge in LH and FSH, potentially restoring or augmenting endogenous hormone production.
Hormonal Suppression: Prolonged exposure is hypothesized to induce receptor desensitization, leading to a sustained decrease in LH and FSH secretion, which in turn lowers testosterone and estrogen levels.
Other Research Areas
Thymus Cells: In murine models, GnRH-analog peptides like Triptorelin have been hypothesized to interact with specific binding sites in the thymus, potentially influencing immune-related processes. However, the exact mechanisms are not yet fully understood.
3. Product Information 🧬
Molecular Formula: C64H82N18O13
Molecular Weight: 1311.4 g/mol
Other Known Titles: 57773-63-4
Important Notice: Triptorelin peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.