Vesugen (20mg)
$69.00 $63.00
Vesugen Product Information
Our Vesugen is a high-purity, synthetic peptide available in a 20mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU for this product is P-VESUGEN-20.
Pricing and Discounts
5-8 units: A 5% discount is applied, with a price of $59.85 per unit.
9+ units: A 10% discount is applied, with a price of $56.70 per unit.
We also offer FREE shipping on all orders over $200.
Vesugen (KED) is a synthetic tripeptide from the Khavinson peptides group. Derived from vascular wall proteins, it's being researched for its potential to influence vascular endothelial cells. Its primary areas of study include its vasoprotective and neuroprotective potential, as well as its possible role as a geroprotector.
1. Mechanisms of Action 🧪
Vesugen’s potential effects are believed to be related to its ability to influence gene expression and cellular function:
Vasoprotective Potential: Vesugen is hypothesized to act on vascular endothelial cells by possibly regulating the expression of the Ki-67 protein, a marker for cell proliferation. By potentially increasing Ki-67 expression, it may help maintain the integrity and function of blood vessel linings, which often decline with age.
Neuroprotective Potential: The peptide is being studied for its potential to restore long-term potentiation (LTP) in the hippocampus and prevent the elimination of dendritic spines, which are crucial for synaptic strength and memory. It is also thought to influence genes and proteins involved in neurogenesis, such as NES and GAP43.
Geroprotective Potential: Vesugen may influence the expression of genes related to aging and apoptosis (e.g., p16 and p21), and potentially stimulate the expression of differentiation factors like CXCL12 in aging cells.
2. Research and Clinical Studies 🔬
Vasoprotective Effects: In vitro studies suggest that Vesugen may help normalize the expression of endothelin-1, which is typically elevated in conditions like atherosclerosis, and could potentially restore cellular interactions by influencing connexin expression.
Neuroprotective Effects: In murine models of neurodegeneration, Vesugen appeared to prevent the elimination of dendritic spines, particularly in the hippocampus, and was associated with a potential for enhanced neuroplasticity.
Geroprotective Effects: Clinical research suggests Vesugen may have an anabolic effect and could be associated with a slowing of the aging process based on biological age indicators. It may also influence the behavior of prostatic fibroblasts, particularly in aged cultures.
3. Product Information 🧬
Molecular Formula: C15H26N4O8
Molecular Weight: 390.39 g/mol
Sequence: Lys-Glu-Asp
Other Known Titles: KED, lysyl glutamyl aspartic acid
Important Notice: Vesugen peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.