VIP (6mg)
$71.00$64.00
Vasoactive Intestinal Peptide (VIP) is a short, naturally occurring peptide hormone that acts as a neurotransmitter, vasodilator, and potential immune regulator. It is being researched for its pleiotropic effects, particularly its anti-inflammatory properties, its role in maintaining the integrity of the blood-brain barrier, and its potential effects on cardiac and behavioral responses.
Product Information
Specification | Details |
SKU | P-VIP-6 |
Purity | >99% |
Form | Lyophilized powder |
Size | 6mg |
Contents | VIP (6mg) |
Pricing
Quantity | Discount | Price (USD) |
Single Unit | N/A | $64.00 |
5 - 8 | 5% | $60.80 |
9+ | 10% | $57.60 |
Chemical Makeup
Specification | Details |
Molecular Formula | C_147H_237N_43O_43S |
Molecular Weight | 3326.8 g/mol |
Other Known Titles | PHM27, Vasoactive intestinal polypeptide |
Research and Clinical Studies
Inflammation & Immunity
VIP is being investigated for its potential to exhibit anti-inflammatory effects in both innate and adaptive immunity. Research suggests it may inhibit the synthesis of pro-inflammatory cytokines and chemokines. In a study on murine models of necrotizing enterocolitis (NEC), VIP exposure reportedly reduced the severity of the condition and decreased levels of inflammatory markers while also helping to preserve the integrity of the intestinal barrier (5, 8).
Neurological & Behavioral Responses
VIP is being researched for its potential neuroprotective effects, particularly its role in supporting the blood-brain barrier (BBB) and blood-spinal barrier (BSB). Research suggests that autoimmune reactions targeting VIP or its receptors may increase the permeability of these barriers, leading to neuroinflammatory processes. Its potential to regulate the immune responses in the brain is under investigation (9).
In behavioral studies, VIP neurons in the hypothalamus have been linked to the secretion of prolactin, a hormone that is associated with behaviors such as affiliation, gregariousness, and aggression. VIP's potential role in regulating circadian rhythms and social behavior is also being explored (13).
Cardiac Health
VIP is being researched for its potential to mitigate cardiac fibrosis, a condition involving the scarring of heart muscle. Studies suggest that VIP may promote a reduction in the expression of angiotensinogen, which is associated with vascular inflammation and fibrosis. This potential action is being compared to that of ACE inhibitors (12).
Disclaimer: VIP peptide is available for research and laboratory purposes only.
